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Biblioteca (s) : |
INIA La Estanzuela. |
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Fecha : |
16/02/2017 |
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Actualizado : |
24/06/2021 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Autor : |
PHAN, T.G; GIANNITTI, F.; ROSSOW,S.; MARTHALER,D.; KNUTSON, T.; LI, L.; DENG, X.; RESENDE, T.; VANNUCCI, F.; DELWART, E. |
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Afiliación : |
FEDERICO GIANNITTI, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
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Título : |
Detection of a novel circovirus PCV3 in pigs with cardiac and multi-systemic inflammation. |
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Fecha de publicación : |
2016 |
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Fuente / Imprenta : |
Virology Journal, 2016 v.13 n. 1. p. 184 |
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DOI : |
10.1186/s12985-016-0642-z |
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Idioma : |
Inglés |
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Notas : |
OPEN ACCESS |
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Contenido : |
Abstract.
Background: Porcine circovirus 2 causes different clinical syndromes resulting in a significant economic loss in the
pork industry. Three pigs with unexplained cardiac and multi-organ inflammation that tested negative for PCV2 and
other known porcine pathogens were further analyzed.
Methods: Histology was used to identify microscopic lesions in multiple tissues. Metagenomics was used to detect
viral sequences in tissue homogenates. In situ hybridization was used to detect viral RNA expression in cardiac tissue.
Results: In all three cases we characterized the genome of a new circovirus we called PCV3 with a replicase and capsid
proteins showing 55 and 35 % identities to the genetically-closest proteins from a bat-feces associated circovirus and
were even more distant to those of porcine circovirus 1 and 2. Common microscopic lesions included non-suppurative
myocarditis and/or cardiac arteriolitis. Viral mRNA was detected intralesionally in cardiac cells. Deep sequencing in
tissues also revealed the presence of porcine astrovirus 4 in all three animals as well as rotavirus A, porcine cytomegalovirus
and porcine hemagglutinating encephalomyelitis virus in individual cases.
Conclusion: The pathogenicity and molecular epidemiology of this new circovirus, alone or in the context of
co-infections, warrants further investigations. |
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Palabras claves : |
ARTERIOLITIS; ARTEROLITIS; CIRCOVIRUS; METAGENÓMICA; METAGENOMICS; MIOCARDITIS; PIG; VASCULITIS. |
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Thesagro : |
CERDO. |
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Asunto categoría : |
L73 Enfermedades de los animales |
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URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/6477/1/Virology-Journal-2016-13.p.184-Phan-et-al..pdf
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Marc : |
LEADER 02290naa a2200361 a 4500
001 1056664
005 2021-06-24
008 2016 bl uuuu u00u1 u #d
024 7 $a10.1186/s12985-016-0642-z$2DOI
100 1 $aPHAN, T.G
245 $aDetection of a novel circovirus PCV3 in pigs with cardiac and multi-systemic inflammation.$h[electronic resource]
260 $c2016
500 $aOPEN ACCESS
520 $aAbstract. Background: Porcine circovirus 2 causes different clinical syndromes resulting in a significant economic loss in the pork industry. Three pigs with unexplained cardiac and multi-organ inflammation that tested negative for PCV2 and other known porcine pathogens were further analyzed. Methods: Histology was used to identify microscopic lesions in multiple tissues. Metagenomics was used to detect viral sequences in tissue homogenates. In situ hybridization was used to detect viral RNA expression in cardiac tissue. Results: In all three cases we characterized the genome of a new circovirus we called PCV3 with a replicase and capsid proteins showing 55 and 35 % identities to the genetically-closest proteins from a bat-feces associated circovirus and were even more distant to those of porcine circovirus 1 and 2. Common microscopic lesions included non-suppurative myocarditis and/or cardiac arteriolitis. Viral mRNA was detected intralesionally in cardiac cells. Deep sequencing in tissues also revealed the presence of porcine astrovirus 4 in all three animals as well as rotavirus A, porcine cytomegalovirus and porcine hemagglutinating encephalomyelitis virus in individual cases. Conclusion: The pathogenicity and molecular epidemiology of this new circovirus, alone or in the context of co-infections, warrants further investigations.
650 $aCERDO
653 $aARTERIOLITIS
653 $aARTEROLITIS
653 $aCIRCOVIRUS
653 $aMETAGENÓMICA
653 $aMETAGENOMICS
653 $aMIOCARDITIS
653 $aPIG
653 $aVASCULITIS
700 1 $aGIANNITTI, F.
700 1 $aROSSOW,S.
700 1 $aMARTHALER,D.
700 1 $aKNUTSON, T.
700 1 $aLI, L.
700 1 $aDENG, X.
700 1 $aRESENDE, T.
700 1 $aVANNUCCI, F.
700 1 $aDELWART, E.
773 $tVirology Journal, 2016$gv.13 n. 1. p. 184
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Registro original : |
INIA La Estanzuela (LE) |
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Registro completo
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Biblioteca (s) : |
INIA La Estanzuela; INIA Las Brujas; INIA Tacuarembó. |
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Fecha actual : |
21/02/2014 |
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Actualizado : |
22/02/2014 |
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Autor : |
Arboleya, J.Suárez, C.González, R. |
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Título : |
Efecto de diferentes dosis y fuentes de nitrógeno en el rendimiento y calidad de la cebolla Granex 33 |
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Fecha de publicación : |
1998 |
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Fuente / Imprenta : |
ln: Día de campo de ajo y cebolla, 1998, Las Brujas, Canelones (UY) Memorias. Las Brujas, Canelones (Uruguay): INIA, 1998. |
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Páginas : |
p. 16-18 |
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Serie : |
(INIA Serie Actividades de Difusión ; 177) |
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Idioma : |
Español |
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Notas : |
INIA Las Brujas |
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Thesagro : |
ALLIUM CEPA; CALIDAD; CEBOLLA; NITROGENO; RENDIMIENTO DE CULTIVOS. |
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Asunto categoría : |
-- |
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Marc : |
LEADER 00714naa a2200205 a 4500
001 1012318
005 2014-02-22
008 1998 bl uuuu u00u1 u #d
100 1 $aARBOLEYA, J.SUÁREZ, C.GONZÁLEZ, R.
245 $aEfecto de diferentes dosis y fuentes de nitrógeno en el rendimiento y calidad de la cebolla Granex 33
260 $c1998
300 $ap. 16-18
490 $a(INIA Serie Actividades de Difusión ; 177)
500 $aINIA Las Brujas
650 $aALLIUM CEPA
650 $aCALIDAD
650 $aCEBOLLA
650 $aNITROGENO
650 $aRENDIMIENTO DE CULTIVOS
773 $tln: Día de campo de ajo y cebolla, 1998, Las Brujas, Canelones (UY) Memorias. Las Brujas, Canelones (Uruguay): INIA, 1998.
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INIA Las Brujas (LB) |
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